ZD-0892 - An Overview
PKA phosphorylates Myosin Binding Protein-C (MyBP-C) and troponin I (TnI) throughout the cardiac myofibril. TnI is the inhibitory part of your trimeric troponin molecule which makes up the Ca2+-swap from the contractile apparatus. TnI binds to TnC when Ca2+ is certain to TnC, although while in the absence of Ca2+, the C-terminus of TnI is released